Approved by the advisory board and accepted for publication on 25. In eight patients, infection preceded hypocomplementemia. In two patients there were no cutaneous lesions at the time of endoscopy, but inflammation of the duodenum, especially of the second part, led to suspicion of the disease. Purpuric rash in all patients, abdominal pain in five, and arthralgia in nine were noted. Henoch schonlein purpura triggered by bee sting is a rare picture.
Henochschonlein purpura synonyms, henochschonlein purpura pronunciation, henochschonlein purpura translation, english dictionary definition of henochschonlein purpura. Iga immunoglobulin a vasculitis causes inflammation and bleeding of the small blood vessels of the skin, joints. Frequently, hsp leads to abdominal pain and intestinal bleeding, renal involvement and joint pain. Henoch schonlein purpura support policy launch welsh. A condition characterized by hemorrhages in the skin and mucous membranes that result in the appearance of purplish spots or patches.
Henochschonlein purpura hsp is an immunemediated vasculitis. These are not repairable and are associated with some loss of function this is why recurrent bouts of hsp can lead to progressive kidney damage and your doctors will monitor your kidney function, presence and quantity of blood. Please use one of the following formats to cite this article in your essay, paper or report. Henochschonlein purpura hsp is an immunologically mediated disease associating purpura plus urticaria, characteristically affecting lower limbs, buttocks, and elbows. Henoch schonlein purpura hsp is the most common form. If you do not have it you can download adobe reader free. To raise awareness of symptoms, long and short term effect of henoch schonlein purpura. Henochschonlein purpura genetic and rare diseases information.
We describe a case of an adolescent male with henochschonlein purpura hsp, presenting with cutaneous and gastrointestinal manifestations. A case of henochschonlein purpura with dilated coronary arteries. Purpura not due to a low platelet count, caused by inflammation in blood vessels of the skin, is the hallmark of hsp. A 57yearold woman presented with classical symptoms of henoch schonlein purpura including arthralgia, abdominal pain, palpable purpuric rash and abnormalities of the urinary sediments. With kidney involvement, there may be a loss of small amounts of blood and.
Henoch schonlein purpura symptoms, diagnosis and treatment bmj best practice swelling around the ankle and foot. Henoch schonlein purpura is the most common childhood vasculitis, but may also affect adults. Serum levels of ch50, c3 or c4 were depressed variously. The tetrad of purpura, arthritis, kidney inflammation, and abdominal pain is often observed. Department of nephrology, childrens hospital, zhejiang university school of medicine, hangzhou 33, china chen. Henochschonlein purpura, henoch schonlein purpura, henochschoenlein purpura, henoch schoenlein purpura, hsp, iga vasculitis, immunoglobulin a. A collection of disease information resources and questions answered by our genetic and rare diseases information specialists for henochschonlein purpura. These files will have pdf in brackets along with the filesize of the download. Biopsies revealed a leukocytoclastic vasculitis in the skin and gastrointestinal tract.
Henochschonlein purpura, sometimes known as hsp, is an autoimmune condition that causes inflammation in the tiny blood vessels of the skin. Hsp presents with purple spots on the skin purpura, arthralgia, digestive problems, and kidney injury. Endoscopy revealed diffuse ulcerations in the stomach, duodenum, and right colon. The iga deposits in vessel walls, associated with the. To open a pdf file you will need compatible software such as adobe reader. Hypersensitivity vasculitis and henoch schonlein purpura. The microscopic hallmark of hsp is the deposition of iga an. Henochschonlein purpura is a particular form of blood vessel inflammation called vasculitis henochschonlein purpura frequently follows an infection of the throat or breathing passages, but it can be induced by certain medications henochschonlein purpura causes skin rash, pain in the abdomen, and joint inflammation the treatment of henochschonlein purpura is directed toward the. A case of henochschonlein purpura linkedin slideshare. It is not clear what triggers the condition, but it often appears a few weeks after an upper respiratory infection such as strep or mycoplasma. Henoch schonlein purpura is a systemic vasculitis mediated by ig a, clinically characterized. Gastrointestinal manifestations of henochschonlein purpura. Henochschoenlein purpura american academy of pediatrics.
Steroid therapy led to complete resolution of the symptoms. A case of henochschonlein purpura hs p gwyneth evans. To share information with other relevant bodies for long and short term benefit of sufferers and their families. Henochschonlein purpura definition of henochschonlein. However, all four elements of this tetrad are not required for diagnosis. In the skin, the disease causes palpable purpura small, raised areas of bleeding underneath the skin, often with joint pain and abdominal pain. When accompanied by a decrease in the circulating platelets, it is. This page includes the following topics and synonyms. The findings in hsp were not different from others with hsp. Hsp occurs more frequently in africans than caucasians b. Henoch schonlein purpura associated with bee sting. It is important to conduct a good medical history in all patients in which henoch schonlein purpura is suspected, with information that includes, exposure to drugs, infectious diseases, and insect bites to decipher the potential trigger. Pdf most of the documents on the racgp website are in portable document format pdf.1358 1176 856 801 43 956 611 452 292 642 81 1106 706 1116 309 315 1175 1573 120 1512 642 1616 383 1563 958 234 839 478 42 817 199 1023 361 456 1026 1316